Essential tremor: diagnosis and management - The BMJ
Essential tremor is one of the most common movement disorders in adults and can affect both children and adults. An updated consensus statement in 2018 redefined essential tremor as an isolated action tremor present in bilateral upper extremities for at least three years. Tremor may also be present in other locations, commonly the neck or the vocal cords. Patients with …
Interpreting an isolated raised serum alkaline phosphatase level in …
Apr 3, 2013 · This article discusses the most common causes of raised alkaline phosphatase levels in an asymptomatic patient and provides advice on the relevant investigations. #### Learning points If alkaline phosphatase is raised in an asymptomatic patient and serum bilirubin, liver transaminases, creatinine, adjusted calcium, thyroid function, and blood count are normal: …
The BMJ: Leading Medical Research, News, Education, Opinion
Use of progestogens and the risk of intracranial meningioma: national case-control study. 2. Association of holidays and the day of the week with suicide risk: multicounty, two stage, time series study. 3. Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials. 4.
Interpreting iron studies | The BMJ
Jun 15, 2017 · Interpreting Iron Studies - June 29, 2017. Alison U Kelly, specialty registrar in chemical pathology1, Stephen T McSorley, clinical research fellow2, Prinesh Patel, general practitioner3, Dinesh Talwar, consultant clinical scientist1. Author affiliations. Department of Biochemistry, Glasgow Royal Infirmary, Glasgow, UK.
Pernicious anaemia - The BMJ
Apr 24, 2020 · Pernicious anaemia is an autoimmune disorder affecting the gastric mucosa with impaired absorption of dietary cobalamin (vitamin B12) resulting in B12 deficiency. Figure 1 depicts the pathophysiology of pernicious anaemia. Vitamin B12 is essential for production of blood cells and myelination of nerves. Its deficiency causes megaloblastic anaemia.
Low back pain and sciatica: summary of NICE guidance - The BMJ
Jan 6, 2017 · Low back pain is the leading cause of long term disability worldwide. 1 The lifetime incidence of low back pain is 58-84%, 2 and 11% of men and 16% of women have chronic low back pain. 3 Back pain accounts for 7% of GP consultations and results in the loss of 4.1 million working days a year. 2 More than 30% of people still have clinically significant symptoms after …
Impact of vaping on respiratory health | The BMJ
Jul 18, 2022 · Widespread uptake of vaping has signaled a sea change in the future of nicotine consumption. Vaping has grown in popularity over the past decade, in part propelled by innovations in vape pen design and nicotine flavoring. Teens and young adults have seen the biggest uptake in use of vape pens, which have superseded conventional cigarettes as the …
Quality improvement into practice | The BMJ
Mar 31, 2020 · Definitions of quality improvement. Improvement in patient outcomes, system performance, and professional development that results from a combined, multidisciplinary approach in how change is delivered. 3. The delivery of healthcare with improved outcomes and lower cost through continuous redesigning of work processes and systems. 4.
Avascular necrosis of the hip | The BMJ
May 30, 2019 · Mean age of presentation in the UK is 58.3 years, with a prevalence of two per 100 000 patients. 2 On average, AVNFH occurs earlier in life than typical osteoarthritis. It is more common in men and the highest prevalence is in men aged 25 to 44 and women aged 55 to 75. 3 In the UK it is the third most common indication for total hip replacement ...
Latest guidance on the management of gout | The BMJ
Jul 18, 2018 · Gout is the most common inflammatory arthritis and its incidence in the UK has steadily increased from 1.5% in 1997 to 2.5% in 2012. 1 2 It is characterised by deposition of monosodium urate crystals in joints and tissues and usually presents with intermittent painful attacks followed by long periods of remission. 3 Here, we review the latest ...