Margaret Qualley Says “The Substance” Was 'Outside My Comfort Zone': 'I Knew It Was Going to Be a Big Challenge' (Exclusive)
In The Substance, Qualley takes on the role of Sue, a more youthful clone of Moore's aging actress who is created by an illicit serum. The film features nudity and plenty of hard to watch moments as the two women, who share one consciousness, inject themselves with the film's titular serum.