A new study has discovered the reason why men tend to sustain more heart muscle damage following a heart attack than women: ...

Sound evidence for fetal/child safety is still lacking for certolizumab, golimumab, abatacept, tocilizumab ... and cytotoxic drugs are used defined pregnancy outcomes cannot be assigned to each of ...

Epigenetic inhibitors as a promising new antimalarial intervention strategy? A new study identifies an inhibitor of gene regulation that specifically kills the malaria pathogen.

Researchers have developed a powerful computational tool, named iDOMO, to improve the prediction of drug synergy and accelerate the development of combination therapies for complex diseases. The study ...

Vincent Gaynor remembers, almost to the minute, when he realized his part in birthing the breakthrough gene therapy Zolgensma ...

Conclusion: Tocilizumab, a novel IL-6R inhibitor, may be beneficial for the treatment of RA in patients who do not respond to methotrexate or disease-modifying antirheumatic drugs. A large ...

The biosimilar of IL-6 inhibitor tocilizumab, called Tyenne (formerly ... turnover of CHF 2.7 billion ($2.95 billion) last year. The drug has long been a major earner for the Swiss group but ...

the general consensus was that the drug class was an R&D dead end. Merck's exit came after other companies including Pfizer, Eli Lilly and Roche all scrapped CETP development programmes following ...

The most recent biologic therapy to receive marketing approval, tocilizumab ... determine factors that favor particular sequences or classes of agents. Moreover, successive biologic use raises ...

Here, azadirachtin is co-assembled with plant secondary metabolites for efficient drug delivery, demonstrating pest management, the activation of plant defensive capacity, while increasing the ...