In 2020-2021, a mysterious skin disease affected fishermen in Senegal. High levels of Portimine A toxin, produced by the ...

In just 3 years, striking new advances have been made in understanding the molecular mechanisms that govern the crosstalk between osteoblasts/stromal cells and hemopoietic osteoclast precursor ...

Objective We investigated genome-wide changes in gene expression and chromatin remodelling induced by tumour necrosis factor (TNF) in fibroblast-like synoviocytes (FLS) and macrophages to better ...

Isomyosamine targets excess pro-inflammatory TNF-alpha, a primary cause of sarcopenia. “Findings from the initial observational study will inform our forward move into multiple planned clinical ...

Melanoma brain metastasis is linked to dismal prognosis and low overall survival and is detected in up to 80% of patients at autopsy. Circulating tumor cells (CTC) are the smallest functional units of ...

Bank of America’s global fund manager survey revealed that respondents still believe U.S. equities will be the best for market returns, while highlighting that defensive sectors such as ...

I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock ...

TNF-α is located upstream of a cascade of molecular signals that induces inflammation and helps activate the process of aging. Many in vivo and in vitro studies have shown that TNF-α plays a ...

Glioblastomas (GBM) are treated with high doses of ionizing radiation (IR). A mechanism by which radiation therapy ...