2 Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology RAS, Moscow, Russian Federation Objectives Neutralisation of tumour necrosis ...

6 Isomyosamine is a novel plant alkaloid small molecule shown to regulate the immuno-metabolic system through the modulation of numerous pro-inflammatory cytokines including TNF-alpha (TNF-α), an ...

But the first iOS 18.4 public beta is finally here, and it brings a lot of big and small changes for iPhone. Here’s what’s new in today’s release. The only big new AI features we’re still ...

I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock ...

Apple today provided developers with the first betas of upcoming watchOS 11.4 and tvOS 18.4 updates for testing purposes. The betas are available to registered developers, and can be downloaded ...

Isomyosamine targets excess pro-inflammatory TNF-alpha, a primary cause of sarcopenia. “Findings from the initial observational study will inform our forward move into multiple planned clinical ...

Tumor necrosis factor alpha (TNFα) is of the most prominent pro-inflammatory cytokines present in MS and EAE, and it also has strong associations with many other chronic pain conditions (51–53).

Baseline iMFI of TNF-α in LEVs, MEVs and SEVs, and the total endo-EV TNF-α concentration, predicted rOA progression with AUCs 0.688, 0.821, 0.821, 0.665, respectively. In contrast, baseline plasma exo ...

Hypothalamic inflammation, indicated by tumor necrosis factor (TNF)-α expression and astrocytosis in the arcuate nucleus, was evident following acute lipid infusion. HFD for 8 weeks suppressed ...