The Cocoon® (from Lonza) is a functionally closed, sterile, efficient manufacturing platform, which combined with our decentralized manufacturing strategy and rapid release testing, enables delivery ...

Rapa creates its therapies by harvesting T cells from the patient, applying its epigenetic reprogramming ... central and stem memory, sets Rapa apart from competing T cell therapies that typically ...

This deficiency prompts a shift from a reliance on AR signaling for cell ... cells can adapt through epigenetic reprogramming. In addition, the study demonstrates that inhibiting TET2 can reverse ...

stem cell aging, epigenetic regulation of stem cells and the development of CRISPR tools for editing the genome of HSCs and for modulating DNA methylation. Katherine King, M.D., Ph.D. began her own ...

To address these challenges, Professor Amrolia has developed a cutting-edge solution that preserves early “stem cell memory” T-cells, which persist longer in patients together with dual ...

Recently, CAR-T cell therapies have emerged ... Furthermore, during the peak expansion of T cells, there was a predominance of central memory T cells (TCM) and stem-like memory T cells (TSCM ...