The research team successfully purified the HSV-1 gB/D48 Fab complex using the 293F ... Subsequently, they resolved the structure of HSV-1 gB bound to D48 at a resolution of 3.04 Å using cryo ...

With Fab 2/6.14, much of the ectodomain was shifted to higher molecular weight and the Fab fragment was substantially depleted ... mAb IgG were immobilized on anti-mouse Fc capture sensors. HAP2 D3 ...

In their study, published on the preprint server bioRxiv*, the researchers describe the method that allows high-resolution structure determination ... (DARPins), Fab fragments of antibodies ...

(Right) Cryo-electron microscopy–determined structure of a membrane protein (orange) embedded in a lipid Salipro environment (blue) with two Fab fragments bound (green). 11 The advantage of the ...

This will ensure successful and compatible transformation of small antibody fragments (single-chain variable fragment (scFv) or Fab fragments ... was used to color the antigen bound structures.

The research team used Kim’s work to reveal the first X-ray crystallography structure of LSD bound to HTR2A. Importantly, Stanford investigators then used cryo-EM to uncover images of a ...

The first structures of an allergen (egg lysozyme ... with Fab. Cartoon representation of a complex between two Fab fragments of a human antibody and two molecules of timothy grass pollen allergen Phl ...

a team of researchers in China have reported the crystal structure of a part of the virus bound to its target on human cells (Science, 2020. DOI: 10.1126/science.abb2762. The snapshot of this ...

Differential scanning fluorimetry involves heating proteins up and observing the precise temperatures at which they lose their structure ... to assess which fragments bound to tankyrase.

Cambridge, UK, 3rd May 2017: Isogenica Ltd, a leader in the design and construction of innovative and highly diverse synthetic antibody libraries, today announces the availability of its new fully ...

Here, we present the crystal structure of the nAChR α1 subunit bound by the Fab fragment of mAb35, a reference monoclonal antibody that causes experimental MG and competes with ~65% of antibodies from ...

Here we show the crystal structure of the HCMV gB ectodomain bound to the Fab fragment of 1G2, a neutralizing human monoclonal antibody isolated from a seropositive subject. The gB/1G2 interaction ...