It is obvious that fab fragments and human antibodies accounted ... Figure 4 shows the search results using the keyword “Lysozyme” in “Protein” column, returning 117 hits. (A) Structure visualization ...

In addition, the variety of molecular types of fragments has increased over time, with Fab the only fragment type first studied in the clinic before 1996. Interestingly, of these Fab candidates ...

The ligand for the T cell receptor (TCR) is a stable complex of a peptide fragment bound in the groove of a major histocompatibility complex (MHC) molecule. The peptides presented by MHC are ...

Toward this goal, a structure of p300 bound to a Lys-CoA bisubstrate HAT inhibitor has been previously elucidated, and the enzyme’s catalytic mechanism has been investigated. Nonetheless, many ...

Using the mouse passive transfer model, the effects of purified human myasthenic immunoglobulin G and of the monovalent Fab fragment on neuromuscular junctions were investigated. Treatment with IgG ...

To gain insight into the chemistry of inhibitor recognition, we determined the crystal structure of the inhibitor preacylation complex of sulbactam, a clinical β-lactamase inhibitor, bound in the ...

To address this problem, this paper presents an algorithm which allows categorization of data fragments based solely on their structure, without the need for any meta data. The algorithm is based on ...

In the brain, the most marked (twofold to threefold) increases occurred in the hypothalamus. In vitro, all OLA measured could be blocked by antibody Fab fragments (Digibind). Conscious rats with CHF ...

Apparently, 3D structure fixed by formaldehyde retained sufficient chromatin proximity after urea purification to enable capture of BUR-interacting fragments. The urea 4C-seq revealed that a ...

Aspirin, heparin, and the chimeric monoclonal antibody antigen-binding fragment 7E3 (c7E3 Fab ... obtained from the angioplasty patients 2 hours after c7E3 Fab infusion showed 65% to 73% bound ...

Dapirolizumab pegol (DZP) is a polyethylene glycol-conjugated anti-CD40L Fab fragment monoclonal antibody ... chimaeras (PROTACs), have become a research hotspot. The chemical structure of TPD ...