In mature neurons, the mitogen-activated protein kinase (MAPK) cascade that leads to the activation of extracellular signal-regulated kinases (ERKs) is stimulated by excitatory glutamatergic ...

Ccr2 recognizes Ccl2, which initiates a signaling cascade to activate the AP-1 complex, which leads to the activation of chemotaxis genes. (B) Further validation of this well-known pathway from ...

“Hereby, neighbouring receptors of the same cells activate each other and trigger a signalling cascade, which finally causes uncontrolled division of cancer cells.” Currently, approaches like ...

Cell signalling is the mechanism by which stimuli are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Types of cell signalling pathways ...

The foundations for this have now been laid. Researchers have found that x-rays trigger a calcium signalling cascade in cells of the immune system. Radiation therapy is a proven approach to ...

Phosphorylation-based ‘signalling’ in multicellular organisms typically triggers a cascade effect, akin to falling dominoes. Prior attempts to leverage this for therapeutic applications in ...

“Hereby, neighboring receptors of the same cells activate each other and trigger a signalling cascade, which finally causes uncontrolled division of cancer cells.” Currently, approaches like ...