Less than a year after approval, Pfizer said it plans to discontinue its hemophilia B gene therapy fidanacogene elaparvovec ...

TEPEZZA, as the first FDA-approved treatment for thyroid eye disease, marks a major breakthrough in managing TED, addressing a critical medical gap for patients who have long had few treatment ...

We demonstrate here that administration of a CD154-specific monoclonal antibody (hu5C8 ... cross-reactive human IgG isotype-specific antibodies. IgG1 antibodies make up at least some component ...

This IgM was recombinantly expressed in serum containing CHO DUKX-B11 cells resulting in cell clones with a maximum specific productivity of 10 pg/cell/day compared to the IgG1 ... D.L. (2004) Phase I ...

In the same way, frozen sections of kidney tissue were incubated with the FITC-conjugated primary antibodies IgG1 (clone R1-12D10 ... After rinsing, T-cells were incubated with goat anti-rabbit ...

Explore the potential of monoclonal antibodies in Alzheimer’s treatment, including breakthroughs and challenges in this ...

The NIH announced that it is launching a phase 2 human challenge trial of AV-1, an investigational monoclonal antibody to ...

No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

This important study explores the conserved role of IgM in both systemic and mucosal antiviral immunity in teleosts, challenging established views on the differential roles of IgT and IgM. The ...

IgG1 antibodies reached ... and fine tailoring of antibody structures to bring new antibodies to the market. Following the success of the first generation of monoclonal antibody blockbusters ...

The inhaled monoclonal antibody IN-006 shows promise in COVID-19 treatment, with high airway antibody levels and a favorable safety profile in healthy adults.