Conventional DMARDs are used as monotherapy or in combination and include methotrexate, leflunomide, azathioprine, ciclosporin, hydroxychloroquine, sulfasalazine, gold and minocycline. Biologic ...

Up to 2018, new DMARD prescriptions were mostly for old-line agents, primarily methotrexate and hydroxychloroquine. Then the rates for these products dipped below 50%, with biologic drugs becoming ...

No significant effect was seen on blood pressure or any measure of arterial stiffness. Also Read: Methotrexate and ...

“Lupus has a broad range of symptoms, often leading it to be called ‘the great imitator’, as it can resemble many other ...

That may be because older DMARDs, namely hydroxychloroquine and methotrexate, came to market when regulatory requirements were different than they are today, Balevic said. “Many of the older ...

Although the chronic autoimmune disease affects thousands, little is known about it and a cure does not currently exist ...

Patients who were receiving methotrexate were randomly allocated to groups who ... Other drugs—penicillamine, indometacin, cyclosporin, hydroxychloroquine, chloroquine, and prednisolone—all did ...

Objective Determine the pharmacokinetics (PK) and exposure–response of hydroxychloroquine (HCQ ... total body weight (WT), concomitant medications belimumab, methotrexate, azathioprine and ...

Chloroquine is still used today but hydroxychloroquine sulfate is usually preferred ... An immunosuppressive, such as methotrexate or mycophenolate mofetil (MMF) A systemic retinoid (such as ...

Eighty seven (67%) patients were receiving DMARDcs: methotrexate: 55 (63%), mean weekly dose: 17.5 mg (SD: 3.5), leflunomide: 22 (25%), hydroxychloroquine: 8 (9%), sulfasalazine: 2 (2%). Fity six (40% ...

Allowed SLE concomitant medications were immunosuppressants (azathioprine, mycophenolate mofetil and methotrexate), antimalarials ... with the most common being hydroxychloroquine (n=13), prednisone ...