This study reports on the adverse effect profile of methotrexate when used in the treatment of RA and PsA in a district general hospital population, and looks at the effect of alcohol consumption ...

2003). HD-MTX used alone is associated with significantly fewer treatment-associated toxic side effects (DeAngelis & Hormingo; Plotkin & Batchelor; Yamanaka & Tanaka). Methotrexate is an ...

The Food and Drug Administration (FDA) has expanded the approval of Jylamvo (methotrexate) to include the treatment of pediatric patients with acute lymphoblastic leukemia (ALL), as part of a ...

Aldeyra Therapeutics, Inc. (Nasdaq: ALDX) (Aldeyra), a biotechnology company devoted to discovering and developing innovative therapies designed to treat immune-mediated and metabolic diseases, today ...

What is leucovorin used for? Leucovorin is commonly used to reduce toxicity, or potential side effects, after receiving a medicine called methotrexate at high doses. Certain forms of leucovorin ar ...

Graft-versus-host disease prophylaxis using posttransplant cyclophosphamide remains a valid option for patients with ...

The following is a summary of “A modified Delphi exercise in physician-perceived risk factors for drug-induced pneumotoxicity ...

Our approach is to develop pharmaceuticals that modulate protein systems, instead of directly inhibiting or activating single protein targets, with the goal of optimizing multiple pathways at once ...

Drugs such as ascorbic acid increase the risk of crystalluria. • The toxicity of methotrexate is increased by sulfadimidine. • Metabolism of phenytoin, tolbutamide, and warfarin are inhibited ...

Background: Methotrexate (MTX) is the primary drug used in the treatment ... MTX levels and laboratory measurements reflecting toxicity outcomes were obtained. Correlations between peak serum MTX ...

Author Stephen King announced Thursday that he is leaving the social media platform X because of its “toxic” environment. “I’m leaving Twitter. Tried to stay, but the atmosphere has just ...