Inflammation plays a crucial role in the development of various diseases, including cancer, allergic diseases, such as asthma, and cardiovascular diseases, such as atherosclerosis and heart failure.

Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

In April 2025, three people in Oregon developed Creutzfeldt-Jakob disease (CJD), a rare, fatal neurological condition that is ...

Talin is a protein that plays an important role in the immune system by activating integrins, receptors that help cells ...

Recent research points to the potential utility of a familiar sounding foe–herpes virus–in the fight against cancer.

Lipid membranes, which form the outer layer of cells, can be engineered to influence cellular functions. For example, ...

Lipid membranes, which form the outer layer of cells, can be engineered to influence cellular functions. For example, adjusting the permeability of ...

The complex interactions between the nervous and immune systems are pivotal in both health and disease, but the cellular and molecular mechanisms underlying ...

A team identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival.

Defects in the signalling pathways associated with these external signals provide the basis for developmental abnormalities, hypertrophy, degeneration, cell transformation and metastasis.