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After its release from promoter‐proximal pausing, RNA Pol II enters into productive elongation. During productive transcription elongation, many factors travel with RNA Pol II and help coordinate ...

However, its regulatory mechanism remains insufficiently understood. Researchers have now uncovered the role of mitochondrial transcription elongation factor in maintaining the balance between mtDNA ...

Together with the higher speed of this elongation speed (Pol II speed), the researchers also observed changes in the so-called splicing, a further work step within the transcription process from ...

Disease‐associated SEC mutations impair phase properties of the elongation droplets and transcription. SPT5 has an intrinsic property to form clusters, and its disordered domain is required for pause ...

Understanding the complex network that regulates transcription elongation requires the quantitative analysis of RNA polymerase II (Pol II) activity in a wide variety of regulatory environments. We ...

What follows is the decision letter after the first round of review.] Thank you for submitting the paper "Dynamics of transcription elongation are finely tuned by dozens of regulatory factors" for ...

Transcription elongation complexes (TECs) are normally extremely stable but remain vulnerable to dissociation by domain-specific transcription termination factors. We report the X-ray crystal ...

In this study, a cytosine methylome map of cotton hypocotyl was developed for the first time to learn the cotton response to methylation for regulating cell elongation under the stress. Detailed ...

Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in ...

Furthermore, TFII-I has been shown to regulate transcription pausing by interacting with proteins that promote or inhibit the elongation step of transcription. Changes in TFII-I expression in humans ...