Discover how cystic fibrosis genetics affect inheritance patterns and symptom. Learn about CFTR mutations, testing options, ...

The protein DNase1 is one of the oldest biological agents in history. It has been on the market since 1958 and is now used, ...

Alyftrek is approved to treat people ages 6 and older who have the genetic condition called cystic fibrosis. Cystic fibrosis happens because of a change in a gene on chromosome 7. This gene is ...

An inhalable medicine with the potential to improve lung disease in people with cystic fibrosis ... known mutations in the CFTR gene, which lead to different levels of the severity of the disease.

“To achieve meaningful AAT expression levels and functionality ... to explore safety and gene delivery at the highest dose of KB408. KB407 for the treatment of cystic fibrosis (CF) Based on ...

The programme utilises Intellia’s CRISPR-based gene editing platform and DNA-writing technology. Credit: Natali _ Mis/Shutterstock. ReCode Therapeutics is set to secure up to $15m in additional ...

This resulted in a high level of gene editing, which boosted levels of the protein made from the cystic fibrosis gene by 5.5-fold, which was enough to restore half of the normal function of the ...

Cystic fibrosis (CF) is a genetic condition ... In someone with CF, this gene does not function as usual, leading to low levels of salt and water outside the cells. The result is unusually thick ...

Cystic fibrosis (CF) is a serious disease that runs in families. It’s caused by a gene that doesn’t work ... There, doctors look for high levels of a chemical called IRT, which may mean ...

People with cystic fibrosis ... incorrect structure. This prevents CFTR from moving to the cell membrane, so it’s never able to complete its function. Because the protein and gene share a ...