acetate CoA-transferase catalyzes the conversion of succinyl-CoA to succinate, coupled with the activation of acetate to acetyl-CoA. We identified the corresponding enzyme in this bacterium as the ...

It may result from a variation in the C7ORF10 gene or the succinyl-CoA:glutarate-CoA transferase (SUGCT) gene. GA1 is a rare inherited metabolic disorder. It results from a deficiency of the GCDH ...

The authors also examined the levels of the Butyryl-CoA-transferase (BcoA) enzyme involved in microbial butyrate synthesis using real-time polymerase chain reaction (PCR). Additionally ...

3-oxoacid-CoA transferase; and TCA, tricarboxylic acid. Illustration Credit: Ben Smith. Cardiac-specific perturbations of key ketolytic enzymes in genetically engineered mice have provided evidence ...

The mechanism Ussher and his team turned their attention to is succinyl CoA:3-ketoacid CoA transferase (SCOT), an enzyme involved in the body’s process of making energy from ketones. They used ...

aurantiacus to better understand the molecular basis of catalysis. We show that Mct is virtually an exclusive intra-molecular CoA transferase and provide atomic-resolution crystal structures of the ...

Kidney stones —formed from minerals and salts—can be painful and costly to treat. Despite decades of research, treatment options are often invasive and evidence reveals a high rate of reoccurrence.

Once in the cell, succinyl‐CoA: phthalate CoA transferase (SPT) converts PA to the unstable phthaloyl‐CoA. The second step in anaerobic PA degradation is its decarboxylation, catalyzed by ...

acetate CoA transferase, which produces butyrate and acetyl-CoA from butyryl-CoA and acetate, is responsible for the final step of butyrate production in bacteria. This study demonstrates that in the ...

We observed a significant increase in the expression of the gene encoding succinyl-CoA:3-oxoacid-CoA transferase, the rate-limiting enzyme for myocardial oxidation of β-hydroxybutyrate and ...