Signalling of angiotensin II via angiotensin II type 1 receptor (AT1) promotes cardiac and renal fibrosis, but its role in lung fibrosis is little understood. Using a rat bleomycin (BLM) induced model ...

From the Department of Medicine, Division of Cardiology, University of Colorado Health Sciences Center, Denver.

Barclays launched a sterling-denominated additional tier 1 (AT1) bond on Thursday. The 6.3-year AT1 bond's first call date is on September 15, 2031, and its initial price talk is in the area of 8. ...

kDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands lDepartment of Biomedical Data Sciences, Section Molecular Epidemiology, Leiden University Medical ...

Abstract—To determine the effects of physiological alterations in endogenous angiotensin II activity on basal renal sympathetic nerve activity (RSNA) and its arterial baroreflex regulation, ...

Now, researchers have taken a decisive step towards understanding how. “This single receptor is responsible for our insatiable, never-ending attraction to sugar,” says Columbia neuroscientist ...

Preclinical data have shown that cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors can inhibit tumour growth and act synergistically with oestrogen receptor antagonists to overcome endocrine therapy ...

The most frequently examined drugs were angiotensin receptor blockers (ARBs) (n=55) and ACE inhibitors (ACE-I) (n=22). More studies reported upregulation than downregulation with ACE-I (n=22), ARBs ...