Defense was optional, but revenge was not. The Detroit Lions avenged last year’s NFC championship game loss to the San Francisco 49ers on Monday, beating the team that ended their 2023 season in ...

The San Francisco 49ers aren't used to sitting at home this time of the year. They're not used to watching football and not participating in January. Since 2019, the Niners have missed just two ...

The San Francisco 49ers concluded their 2024 season on the road against the Arizona Cardinals. Among the long list of of injured players not suiting up for the season finale was QB1 Brock Purdy ...

The San Francisco 49ers missed the playoffs entirely after making it to the Super Bowl last season. This offseason, they will have some big questions to answer as they turn their attention to free ...

Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ season finale in Arizona against the Cardinals with a leg injury.

San Francisco 49ers running back Isaac Guerendo gave a positive update on his knee injury Monday, noting he did not tear his ACL as some had speculated: ACL is good, thank you GOD. I'll be back ...

The 49ers lost another running back Sunday. Isaac Guerendo was carted off the field with injuries to his left knee and ankle. The team ruled out his return today. Guerendo was injured on the team’s ...

The 49ers will have tight end George Kittle for today’s season finale against the Cardinals. Kittle was questionable with ankle and hamstring injuries after not having a full practice this week. The ...

The Arizona Cardinals and San Francisco 49ers play on Sunday, Jan. 5 in a game on the NFL Week 18 schedule. Here's a look at the time, TV channel and broadcast information for the Week 18 NFL game ...

After scraping with Arizona Cardinals cornerbacks on back-to-back plays, San Francisco 49ers wide receiver Jauan Jennings was ejected from Sunday’s game, costing him a chance at a 1,000-yard season.

“But I'm proud of them. I really am. They fought, they battled. ... To put that kind of effort against the 49ers, a well-coached, tough, physical team, I thought that was cool to see.