Merck’s Keytruda holds on to the top spot while AbbVie’s Humira—once the world’s top-selling drug—continues to cede its ...

The resulting paper, "HLA DQA1*05 and risk of anti-TNF treatment failure and anti-drug antibody development in children with Crohn's Disease," appears in the American Journal of Gastroenterology.

There are currently four monoclonal antibodies available that are directed against TNF: infliximab, adalimumab, golimumab and certolizumab. All of these agents are efficacious in RA, with clinical ...

(In justifying to Centocor why it would be wise to invest in the development of antibodies to lymphotoxin and TNF, I mentioned the possibility of their therapeutic usefulness in autoimmune diseases.) ...

A study by Strangfeld et al. adds specificity by showing a moderately increased risk of herpes zoster in patients receiving anti-TNF antibody treatment, and raises the question of whether live ...

Since the 1990s, numerous studies have been performed to evaluate the effect of monoclonal antibodies on TNF-α and soluble receptor fusion proteins on cytokine levels and survival of septic patients.

Biologics are medications made from antibodies that prevent certain ... Three types of biologics used to manage UC include: anti-tumor necrosis factor (anti-TNF) agents integrin receptor ...

Contrary to established dogma, the spleen is not the principal source of the pro-inflammatory cytokine called tumor necrosis factor (TNF), which drives the sort of system-wide inflammation seen in ...

BALTIMORE--(BUSINESS WIRE)--TNF Pharmaceuticals, Inc. (Nasdaq: TNFA) (“TNF” or the “Company”), a clinical stage biopharmaceutical company committed to ...