Silica is a crucial mineral for maintaining the health of our bones, skin, and hair. It is highly recognized for enhancing collagen production, promoting joint health, and fortifying the immune ...

The cGAS-STING signalling pathway has a central role in the innate immune response to extrinsic and intrinsic sources of cytoplasmic dsDNA. At the core of this pathway is cGAS-dependent production of ...

With the BioPhotometer plus, Eppendorf offers a compact UV/Vis photometer for use in molecular biology, biochemistry and cell biology. The photometer provides instant, out-of-the-box access to 32 ...

Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States Neuroscience Interdepartmental Program, University of California, Los ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. In the preceding few decades, the emergence of RNA-based ...

This review discusses critical molecular mechanisms by which exogenous particles (i.e., silica, asbestos, carbon nanotubes, titanium dioxide, aluminum-containing salts) and endogenous particles (i.e., ...

Various sources, including dead cells, tumor cells, DNA and retroviruses, and self-DNA, can release dsDNA into the cytoplasm, triggering cGAS activation. Upon binding to dsDNA, cGAS catalyzes the ...