Meanwhile, Novartis seems to be leading the pack with TNO155, which has advanced to phase 2 testing as a monotherapy and is also in combination studies with Mirati's KRAS drug adagrasib.

Among patients with early-stage triple-negative breast cancer, a beneficial pathologic complete response rate was higher in patients with BRCA1/2 mutations. Among patients with early-stage ...

The present study was designed to address the mutations as a reflection of genome sequence in the spike protein of SARS-CoV-2 compromising 1,273 A.As during the different time points of vaccinations.

SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors.

A new study published in PLOS Genetics has identified an extreme mutational hotspot within the genome of Pseudomonas ...

Acquired DNA mutations found in the SERPINA1 gene can protect liver cells from damage in patients with alpha-1 antitrypsin ...

Research reveals how a specific mutation in a protein called TRAF1 can shut down an overactive immune response, dramatically reducing inflammation in mice. This discovery could pave the way for a new ...

In a study comparing the glioma tumors of firefighters and non-fighters, researchers found a mutational signature tied to exposure to haloalkanes, which are used in flame retardants, fire ...

Having two copies of the MTHFR gene mutation may raise your risk for certain health conditions, though more research is needed. You may have the mutation and not find out unless you undergo ...