Less than a year after approval, Pfizer said it plans to discontinue its hemophilia B gene therapy fidanacogene elaparvovec ...

UTRECHT, The Netherlands and CAMBRIDGE, Mass., Feb. 18, 2025 (GLOBE NEWSWIRE) -- Merus N.V. (Nasdaq: MRUS), a clinical-stage oncology company ...

This marks the second BTD for petosemtamab in HNSCCUTRECHT, The Netherlands and CAMBRIDGE, Mass., Feb. 18, 2025(Nasdaq: MRUS), a clinical-stage oncology company developing innovative, full-length mult ...

This important study explores the conserved role of IgM in both systemic and mucosal antiviral immunity in teleosts, challenging established views on the differential roles of IgT and IgM. The ...

Each mode is usually self-explanatory, such as “D” for Drive or “R” for Reverse. However, some vehicles have an additional setting—“L”—that may not be immediately clear. Discover what “L” stands for, ...

We demonstrate here that administration of a CD154-specific monoclonal antibody (hu5C8 ... cross-reactive human IgG isotype-specific antibodies. IgG1 antibodies make up at least some component ...

A thyroglobulin antibody (TgAb) test looks for certain antibodies that attack the thyroid. The presence of TbAb in high levels may indicate that someone has an autoimmune condition. To conduct a ...

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Anti-malarial monoclonal antibodies (mAbs) are another promising new tool that have been shown to be safe and efficacious against infection with Plasmodium falciparum, which is the deadliest ...

Antibodies, also known as immunoglobulins (IGs ... lead to four distinct IgG subclasses: IgG1, IgG2, IgG3, and IgG4, each with unique effector functions. Protein antigens typically elicit ...

Results: The results showed that the CD3×EpCAM BsAb could activate and recruit T cells via binding colorectal cells and T cells, which could lead to more potent cytotoxicity to various colorectal cell ...

The 6E5 mAb had a high affinity (3.7 × 10 8 L/mol) to OTA, and also showed similar binding ... 2 O), Goat anti-mouse-peroxidase conjugate (IgG-HRP), mouse monoclonal antibody isotyping kit (IgG1, ...