A 1-year course of methotrexate may help prevent the development of ACPA-negative RA among patients with clinically suspect arthralgia at high-risk for the disease.

Methotrexate is a cornerstone of therapy worldwide for juvenile idiopathic arthritis, yet there remains vast variability in drug dosing and administration, as well as unpredictable outcomes on the ...

This study reports on the adverse effect profile of methotrexate when used in the treatment of RA and PsA in a district general hospital population, and looks at the effect of alcohol consumption ...

Testing new substances in animals is a regulatory cornerstone of drug development. At the same time, the development of animal free testing methods is progressing. In this context the pharmaceutical ...

Predictors of MTX monotherapy treatment success among patients with RA include low disease activity, normal body weight and ESR levels, and fewer tender joints.

Objectives Secondary prevention of rheumatoid arthritis (RA) is generally considered potentially impactful because the entire ...

The following is a summary of “High serum levels of CXCL13 predict lower response to csDMARDs in both ACPA-positive and ACPA-negative early rheumatoid arthritis,” published in the October 2024 issue ...

WASHINGTON, Nov. 16, 2024 /PRNewswire/ -- Physicians are learning how to better support the needs of people with rheumatoid arthritis (RA) from online search trends, according to a new study from ...

like methotrexate for rheumatoid arthritis. In more severe cases, biologics may be used to target specific components of the immune system. Physical therapy helps strengthen muscles around the ...

Former Strictly Come Dancing star Adam Thomas has opened up about his struggle with "pretty unbearable" pain due to arthritis ...

Sixty-nine-year-old Mary Anne Laporte was diagnosed with knee arthritis 15 years ago. For years, she kept the pain under control with steroid injections and physical therapy, but when she began ...

The FDA has approved an extended indication of methotrexate (JYLAMVO; Shorla Oncology) to include pediatric patients with acute lymphoblastic leukemia (ALL) and polyarticular juvenile idiopathic ...