Conventional DMARDs are used as monotherapy or in combination and include methotrexate, leflunomide, azathioprine, ciclosporin, hydroxychloroquine, sulfasalazine, gold and minocycline. Biologic ...

Up to 2018, new DMARD prescriptions were mostly for old-line agents, primarily methotrexate and hydroxychloroquine. Then the rates for these products dipped below 50%, with biologic drugs becoming ...

“Lupus has a broad range of symptoms, often leading it to be called ‘the great imitator’, as it can resemble many other ...

Although the chronic autoimmune disease affects thousands, little is known about it and a cure does not currently exist ...

and hydroxychloroquine (StopRA) proved ineffective in preventing the onset of RA, and both trials were stopped early. Rituximab and methotrexate (MTX) both delayed the onset of RA, but the effect ...

Background: Emerging evidence during the last two decades supports a pivotal role of Interleukin 6 (IL-6) in the pathogenesis of Systemic Sclerosis (SSc). Standard immunosuppressive agents are often ...

JIA was discovered at steinbrocker functional stages II and III. Treatment included NSAIDs 72.72% (8), corticosteroid therapy combined with methotrexate and hydroxychloroquine 54.54% (6) and ...

JIA was discovered at steinbrocker functional stages II and III. Treatment included NSAIDs 72.72% (8), corticosteroid therapy combined with methotrexate and hydroxychloroquine 54.54% (6) and ...

Patients who were receiving methotrexate were randomly allocated to groups who ... Other drugs—penicillamine, indometacin, cyclosporin, hydroxychloroquine, chloroquine, and prednisolone—all did ...

Objective Determine the pharmacokinetics (PK) and exposure–response of hydroxychloroquine (HCQ ... total body weight (WT), concomitant medications belimumab, methotrexate, azathioprine and ...