Discover how biotechs and big pharma are developing novel treatments for high cholesterol with a range of different targets.

LDL particle number and size analysis examines the quantity and characteristics of LDL particles rather than just their cholesterol content. Some families carry genetic tendencies toward numerous ...

For almost 60 years, measuring cholesterol levels in the blood has been the best way to identify individuals at high risk of ...

Although high LDL-C levels are not a component of insulin resistance, small LDL particle size is associated with the atherogenic dyslipoproteinemia of insulin resistance. Small LDL particles carry ...

Background— Nuclear magnetic resonance (NMR) spectroscopy measures the number and size of lipoprotein particles instead ... in vapor-phase liquid nitrogen (−170°C). Samples for lipoprotein particle ...

Our results reveal a significant and progressive decrease in the molar content of α- and γ-tocopherol in both LDL and HDL subspecies, with diminution in particle size and lipid core from light to ...

High cholesterol is often painted as a one-way ticket to heart disease, but science and real-life stories tell a more complex ...

Clin Lipidology. 2013;8(1):69-79. Direct measurement of ApoB and LDL-P provides another option to assess atherogenic particle concentration. Although the bias and imprecision of ApoB measurement ...

The continuous, solid-phase system achieved a refolding yield of approximately 100% by gradually pumping lysozyme through the ...

Clin Lipidology. 2009;4(5):565-571. Given this information, there remains a key question: will ERN's ability to change LDL-P result in a measurably favorable change in cardiovascular outcomes?