‘Black box’ safety warning to be removed from hormone therapy for menopause

In a pivotal move, the US Food and Drug Administration on Monday said it is taking steps to remove the lengthy “black box” warning on many hormone treatments for women with menopause symptoms — a ...

FDA removes 'black box' warning label on hormone replacement therapy for menopause

The Food and Drug Administration will remove the "black box" warning from hormone replacement therapy (HRT) products for ...
Public Broadcasting Service (PBS)

FDA head explains decision to drop ‘black box’ warnings from menopause hormone treatment

The FDA announced it would begin asking drug companies to remove so-called “black box” warnings for hormones prescribed to ...

F.D.A. Will Remove Black Box Warnings From Hormone Treatments for Menopause

The benefits of hormone replacement have been underappreciated, Dr. Marty Makary, the agency’s commissioner, said on Monday. Critics described evidence for the change as insufficient.
eLife

Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites

Acetylation of lysine residues in the tail domain of histone H3 is well characterized, but lysine residues in the histone globular domain are also acetylated. Histone modifications in globular domain ...