The use of high-dose methotrexate (HD-MTX) has improved survival rates. This article describes the experience of a patient treated with HD-MTX and outlines the essential aspects of care for the ...

Methotrexate is generally well tolerated in doses given to treat ectopic pregnancy. High-dose methotrexate has been associated with bone marrow suppression, hepatotoxicity, stomatitis, pulmonary ...

Leucovorin is turned into folic acid in your body. Folic acid can protect your healthy cells from the effects of high-dose methotrexate. When leucovorin is used for cancer, it can make certain ...

My daughter's diagnosis of a rare and aggressive brain tumor at 3 years old made me strongly consider whether or not to have her treated with radiation.

Many types of medications, including over-the-counter (OTC) and prescription drugs, can help relieve joint pain due to ...

We describe a case of a patient with medulloblastoma aged 18 months at the time of oncological diagnosis who was treated with high-dose chemotherapy followed by HSCT and who developed CCM two years ...

Typhoid vaccines prevent typhoid fever, a potentially fatal bacterial infection. While typhoid vaccination is not a routine immunization for people in the United States, it is recommended for anyone ...

Objectives An increased risk of tuberculosis (TB) has been reported in patients treated with TNF-α antagonists, an issue that has been highlighted in a WHO black box warning. This review aimed to ...

A commissioning policy is a document that defines access to a service for a particular group of patients. A NICE Technology Appraisal Guideline on the same topic will replace, or be incorporated into, ...