a proposed golimumab biosimilar to SIMPONI® and SIMPONI ARIA®. Stay tuned to Big Molecule Watch for further regulatory updates on biosimilars.

Takeda has returned to BridGene Biosciences for another small-molecule collaboration—this time focused on immunology as well as neurology. BridGene’s pursuit of undruggable targets is enabled ...

Single-molecule biophysics is the study of the dynamics and interactions of individual biomolecules to understand how they carry out their functions in living cells. For example, monitoring the ...

The result is a three-dimensional Fourier, or electron-density, map of the unit cell, which for the first time reveals the general nature of the tertiary structure of a protein molecule.

Simponi and Simponi Aria (golimumab) can cause mild to serious side effects. A more common side effect includes upper respiratory infection. If side effects from the drug become difficult to ...

When a hydrogen atom combines with a hydroxyl molecule it forms a molecule of water, the most essential molecule for life as we know it. Thus, the range of frequencies from 1420 to 1720 MHz is called ...

The high determinant density model, in which the structure of the allogeneic MHC molecule governs T-cell recognition; [34] The multiple binary complex model, in which alloantigen recognition is ...

(NewsNation) — Researchers at Stanford Medicine have discovered a naturally occurring molecule they believe is similar to the active ingredient in the same diabetes drugs that have shown weight loss ...

The FDA unveiled the Chemical Contaminants Transparency Tool, a searchable online database that provides a list of chemical contaminant types and levels used to evaluate possible harm in foods ...

The DMARDs are divided into conventional synthetic (cs) DMARDs (such as methotrexate, leflunomide and sulfasalazine), biological (b) DMARDs [TNF inhibitors (infliximab, etanercept, adalimumab, ...

Correspondence to Professor Josef S Smolen, Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Waehringer Guertel 18-20, Vienna A-1090, Austria; ...