ABSTRACT: Background: Univentricular hearts represent 0.5% - 1.5% of congenital heart defects. They are a heterogeneous group of malformations with the common feature of a single dominant ventricle.

Objectives: To determine physical activity levels in paediatric patients who underwent the Fontan procedure, and their relationship to functional status and exercise capacity. Study Design: We studied ...

It is challenging to ascertain whether these protein changes are a consequence of the Fontan circulation or merely an associated phenomenon. Second, the statistical power was limited, with thousands ...

By applying a state‐of‐the‐art characterization of the plasma proteome, this study aimed at providing a comprehensive insight into the proteomic impact of living with a Fontan circulation. This study ...

The Fontan operation is now among the most common procedures performed to treat complex congenital cardiac defects not amenable to biventricular repair. The advent of the Norwood procedure to ...