Leucovorin is turned into folic acid in your body. Folic acid can protect your healthy cells from the effects of high-dose methotrexate. When leucovorin is used for cancer, it can make certain ...

The use of high-dose methotrexate (HD-MTX ... its chemotherapeutic effect by counteracting and competing with folic acid in cancer cells, resulting in folic acid deficiency and cell death.

High-dose methotrexate has been associated with bone ... Patients receiving methotrexate should stop prenatal vitamins or folic acid supplements. During treatment with methotrexate, ß-hCG levels ...

Doses may range from once daily to 2 ... develop in the first 2 to 3 years of the condition. Taking a folic acid supplement with methotrexate may reduce the side effects. However, an individual ...

Initially 12g/m 2 IV infusion over 4 hours; may be increased to 15g/m 2; see literature for leucovorin rescue dosing with high-dose methotrexate. Be fully familiar with this drug's toxicity before ...

Vit.A (as beta carotene) 1100 IU, thiamine 1.6mg, riboflavin 1.8mg, niacinamide 15mg, pyridoxine 2.5mg, folic acid 1mg, Vit.B12 12mcg, Vit.C 30mg, Vit.D 1000 IU, Vit ...

Folic acid can protect your healthy cells from the effects of high-dose methotrexate. When levoleucovorin is used for cancer, it can make certain chemotherapies work better to target and kill the ...