Folic acid is the synthetic form of folate used ... Folate supplements may interfere with certain medications such as methotrexate, diuretics, NSAIDs, immunosuppressants and some anti-seizure ...

Methotrexate is an antimetabolite that penetrates ... MTX exerts its chemotherapeutic effect by counteracting and competing with folic acid in cancer cells, resulting in folic acid deficiency ...

Leucovorin is turned into folic acid in your body. Folic acid can protect your healthy cells from the effects of high-dose methotrexate. When leucovorin is used for cancer, it can make certain ...

Methotrexate is a folic acid antagonist. It works by inhibiting the synthesis of purines and pyrimides and therefore interfering with DNA synthesis. Methotrexate affects rapidly dividing cells and ...