These results from the TROPION-Lung01 Phase III trial, which compared the standard of care in second-line docetaxel, a type of chemotherapy, with Dato-DXd, an antibody drug conjugate, in patients ...

Docetaxel is a chemotherapy drug that is used ... neutropenia, allergic reaction, fluid retention, edema, dizziness, hair loss, diarrhea, cramping and dysphagia, compared with those who took ...

Reported adverse effects of docetaxel include hypersensitivity reactions (presenting as flushing, skin reactions, hypotension and bronchospasm), bone marrow suppression (neutropenia, thrombocytopenia, ...

You have cyclophosphamide as a slow injection or a drip into your vein. Taxotere can cause an allergic reaction. To try to prevent this, your doctor or nurse gives you steroid tablets to take. You ...

When should Docetaxel not be taken? (Contraindications) Contraindicated in patients with previous severe hypersensitivity reaction to this drug, the solvent or polysorbate 80, severe decrease in ...

For each patient, the investigators read the nursing note to look for evidence of any documented adverse effect that occurred after beginning docetaxel or paclitaxel infusion. Because of the high ...

hypersensitivity reaction, and pulmonary infiltrates (fatal in two patients). Late toxicity of esophageal stricture occurred in five patients. Esophagitis and neutropenia are the dose-limiting ...

Theratechnologies’ SORT1-targeting peptide-drug conjugates TH1902 (peptide-docetaxel conjugate) and TH1904 (peptide-doxorubicin conjugate) strongly inhibit VM at very low doses. When ...

These results demonstrate that TH1902 has better anti-metastatic activity when compared to docetaxel alone when administered at an equimolar concentration in a lung metastasis cancer model ...

Treatment with datopotamab deruxtecan (Dato-DXd), a novel Trop-2 directed antibody-drug conjugate ... or death compared to patients treated with docetaxel. "While there was an overall reduction ...