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Reported adverse effects of docetaxel include hypersensitivity reactions (presenting as flushing, skin reactions, hypotension and bronchospasm), bone marrow suppression (neutropenia, thrombocytopenia, ...
For each patient, the investigators read the nursing note to look for evidence of any documented adverse effect that occurred after beginning docetaxel or paclitaxel infusion. Because of the high ...
hypersensitivity reaction, and pulmonary infiltrates (fatal in two patients). Late toxicity of esophageal stricture occurred in five patients. Esophagitis and neutropenia are the dose-limiting ...
These results from the TROPION-Lung01 Phase III trial, which compared the standard of care in second-line docetaxel, a type of chemotherapy, with Dato-DXd, an antibody drug conjugate, in patients ...
Docetaxel is a chemotherapy drug that is used ... neutropenia, allergic reaction, fluid retention, edema, dizziness, hair loss, diarrhea, cramping and dysphagia, compared with those who took ...
When should Docetaxel not be taken? (Contraindications) Contraindicated in patients with previous severe hypersensitivity reaction to this drug, the solvent or polysorbate 80, severe decrease in ...
First study of patients with metastatic prostate cancer to evaluate standard-of-care chemotherapy (docetaxel) combined with an antibody drug conjugate (PDS0301). Decrease in prostate specific ...
Treatment with datopotamab deruxtecan (Dato-DXd), a novel Trop-2 directed antibody-drug conjugate ... or death compared to patients treated with docetaxel. "While there was an overall reduction ...