and daratumumab (PDB: 7DHA) target CD38 at non-overlapping epitopes. These two antibody-antigen complexes were determined independently, and their structures do not influence each other. Case 2 : When ...

A new four-drug combination is highly effective and safe in patients with newly diagnosed multiple myeloma, according to data presented at the annual meeting of the American Society of Clinical ...

How cancer patients relying on daratumumab feel physically before starting the therapy can predict how long they will live and how well they will respond to the anti-multiple myeloma (MM ...

Pieter Sonneveld, MD, PhD, professor of hematology and chair of the Erasmus MC Cancer Institute in Rotterdam, Netherlands, discussed the continued use of subcutaneous daratumumab following initial ...

Can you describe the modeling strategy used to predict long-term outcomes for patients receiving frontline quad therapy of daratumumab plus VRd? In the PERSEUS trial for transplant-eligible ...

In August 2012, Janssen Biotech, Inc. and Genmab A/S entered a worldwide agreement, which granted Janssen an exclusive license to develop, manufacture and commercialize daratumumab. Systemic ...

Most employees typically fall into the "Significant Impact" category. Under the new structure, managers will be allowed to assign the coveted "Outstanding Impact" rating to more employees ...

“And now that we have this structure, perhaps we can find ways to modulate its function.” For example, compounds that target the receptor could alter how natural sugars are sensed by taste ...

Maxine Waters, will block efforts to hold a joint hearing between her committee and the House Agriculture Committee on Monday's newly unveiled market structure discussion draft bill. Under House ...

Crews are on the scene of a structure fire in Avondale Saturday evening, according to dispatch.The fire started around 8 p.m. in the 800 block of Hutchins Avenue.It is unclear what caused the fire ...

Amazon's new pay model rewards top performers, cuts first-time achievers The revised structure places greater emphasis on an employee's rating history rather than just current performance.