DNA methylation is the covalent addition of methyl groups to DNA bases, typically the cytosine of CpG dinucleotides. It is catalyzed by methyltransferase enzymes using a S-adenosyl methionine ...

Another seminal study investigated the DNA methylation patterns of 450 000 CpG-sites across whole-blood samples from 656 individuals aged 19–101. 34 More than 70 000 CpG-sites whose ...

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