On the basis of recent data, a new hypothesis is put forward whereby centrosome abnormalities could have a role in tumour development — not by causing aneuploidy, as proposed by the classical ...

Centrosome amplification and aberrant expression of its associated proteins such as Polo-like kinases (PLKs), Aurora kinases (AURKs) and Cyclin-dependent kinases (CDKs) have been observed in various ...

Enhanced expression can also lead to centrosome duplication, genomic instability, mitotic check point failure, abrogated kinetochore attachment, incorrect spindle stress, and chromosomal misalignment ...

With the theoretical part extended, this paper would be of interest to cell biologists and biophysicists working on asymmetric partitioning during cell division. Asymmetric partition of fate ...

Your Artstor image groups were copied to Workspace. The Artstor website will be retired on Aug 1st. Memoirs of the American Academy of Arts ... Memoirs of the American Academy of Arts and Sciences Vol ...

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