“In non-human primates, the vector achieved robust brain transduction via intra-CSF delivery – a route long viewed as promising but historically constrained by limited efficacy and off-target effects.

“In non-human primates, the vector achieved robust brain transduction via intra-CSF delivery – a route long viewed as promising but historically constrained by limited efficacy and off-target ...

The researchers injected some of the animals with the treatment directly into a space at the back of their skulls where cerebrospinal fluid flows from the brain to the spinal cord (mimicking ...

A University of California–led case report in Emerging Infectious Diseases, describes a 58-year-old woman who, an estimated ...

They did this to study the drug’s pharmacokinetics via each route, as well as safety ... of fluid from outside to inside the brain. Supporting this, in placebo controls, ventricular volume and ...