The growth factor Angiotensin-2 signals through Angiotensin receptor type 1 (AT1-R) in a broad range of cell types and tumours and through the type-2 receptor (AT2-R) in a more restricted group of ...

with alveolar type 1 (AT1) cells reprograming into alveolar type 2 (AT2) cells (two very different lung alveolar epithelial cells), promoting cell regeneration, rather than AT2 cells differentiating ...

These study findings, published today in Cell Stem Cell, show that the long-held assumption that AT1 and AT2 cells behave the same way in children and in adults is untrue. The lung alveolus is ...

Researchers have now grown lung organoids from human embryonic stem cells (hESCs) that, after implantation in mice, can develop mature alveolar type 1 (AT1) and AT2 cells and architecture ...

The group then turned to organoid culture to test the ability of subpopulations ... whereas adding WNT inhibitors promoted the differentiation of AT2 cells into AT1 cells. This result underscores ...

The lining of the alveoli is made of two distinct types of cells — alveolar type 1 (AT1) and alveolar type 2 (AT2). And while they’re similarly named, these two cells couldn’t be more different. AT1 ...

The protein, called AT2, is one of ... signals in the cell. "This information then could be used to design selective drugs that specifically target AT2 and not AT1 or other GPCRs," he explained.

The lining of the alveoli is made of two distinct types of cells - alveolar type 1 (AT1) and alveolar type 2 (AT2). And while they're similarly named, these two cells couldn't be more different.

These study findings, published today in Cell Stem Cell, show that the long-held assumption that AT1 and AT2 cells behave the same way in children and in adults is untrue. The lung alveolus is ...

The lining of the alveoli is made of two distinct types of cells -- alveolar type 1 (AT1) and alveolar type 2 (AT2). And while they're similarly named, these two cells couldn't be more different.