Their model was able to identify antibody structures that would be the most successful, much more accurately than traditional ...

For experimental screening studies in particular, the model assists in understanding the structure of antibodies’ hypervariable regions, how tightly they bind and how well they neutralize antigens.

Immunotherapies use antibodies—proteins that bind to ... already trained on a vast amount of protein structure data. The model used sequences to predict how proteins fold and interact ...

A recently developed diffusion model for protein structures ... The team also purified the antibody-flu virus protein complex and determined its structure, showing it largely reflected the ...

Researchers show that analyzing the 3D shapes of antibodies, not just their genetic sequences, can better group functionally ...

structure-guided approach to elicit the right kinds of antibodies." The approach paid off. Several of the vaccinated animal ...

Although their role is universal, antibody structure varies in different animals. In a new study, researchers have analyzed the antibody Immunoglobulin M in rainbow trout to shed some light on why ...

Although their role is universal, antibody structure varies in different animals. In a new study, researchers have analyzed the antibody Immunoglobulin M in rainbow trout to shed some light on why ...