The 49ers snagged a third-round comp pick in the 2025 draft when DeMeco Ryans and Ran Carthon were both hired in the same offseason. Ryans went to the Houston Texans as their head coach. Carthon went to the Tennessee Titans as their general manager.

The 49ers are going all-in for a Robert Saleh reunion. The former New York Jets head coach has an offer on the table from San Francisco to become the highest-paid defensive coordinator in the NFL, according to The Athletic’s Matt Barrows.

The 49ers have been trying in vain to replace DeMeco Ryans since he left last year. Under Ryans, they had the no. 1 defense in the NFL.

The San Francisco 49ers are on the search for a defensive coordinator once again after firing Nick Sorensen following just one season in that role.

After struggling down the stretch, the Houston Texans turned things around in a big way with their 32-12 wild-card win over the Los Angeles Chargers on Saturday -- and 49ers star Fred Warner largely credits DeMeco Ryans.

Jim Harbaugh’s Los Angeles Chargers travel to Houston to take on DeMeco Ryans’s Texans. Both teams enter Saturday with quarterbacks who were drafted early in the first round. C.J. Stroud’s sophomore season has seen some regression,

The 49ers’ 2024 season is over after they lost Sunday to the ... 43 and 75 in the second and third rounds, and pick up a compensatory third-rounder for having DeMeco Ryans and Ran Tarthon hired away as the Texans’ head coach and Titans’ GM, respectively.

The San Francisco 49ers added a new first priority to their offseason plate when head coach Kyle Shanahan fired defensive coordinator Nick Sorensen. They’ve been swift in looking for Sorensen’s replacement, completing their first two interviews Thursday with others likely coming soon.

A couple years ago, the 49ers probably could have had whichever defensive coordinator they wanted. Now that job might not be so desirable.

DeMeco Ryans and Andy Reid go back to their days in Philadelphia. Now the Texans' coach will try to take his old boss to get Houston to its first AFC title game

Sorensen spent just one season as the 49ers defensive coordinator after the team fired Steve Wilks last season. The 49ers ranked eighth in defensive yards, but allowed the fourth most points in the NFL. The 49ers struggled especially in the fourth quarter, being outscored by 52 points in the final frame.

The San Francisco 49ers have removed Nick Sorensen ... Wilks was the DC for one season in 2023 after succeeding DeMeco Ryans, now the head coach of the Houston Texans. Sorensen joined the 49ers in 2022 as a defensive assistant after serving as an assistant ...