The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is ...

De Duve named these new organelles "lysosomes" to reflect their lytic nature. That same year, Alex Novikoff from the University of Vermont visited de Duve´s laboratory. An experienced ...

In a paper published in Nature Communications, researchers from Kyushu University, using cultured cells and mice, found that the lipid peroxidation of the lysosomes—the organelle responsible for ...

a professor of cell death and metabolism at the Danish Cancer Society Research Centre, who was not involved in the work. Research had already established one way that cells repair leaky lysosomes.

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Nature Communications on how the targeted suppression of lysosome function may lead to brain cancer therapy.

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes.

Pancreatic cancer is a leading cause of cancer-related death, with a five-year survival rate of 13%. The high mortality is ...

Of the 190 genes that decreased activity, the top hit goes by the mouthful “copper metabolism MURR1 domain-containing 3 ... and cathepsin B in the knockout cell lysosomes. These cells also cleaved ...

In a paper published in Nature Communications, researchers from Kyushu University, using cultured cells and mice, found that the lipid peroxidation of the lysosomes—the organelle responsible for ...