So those would be the serious concerns associated with biologic agents like TNF inhibitors. Narrator And if you are unlucky to have one of these serious side effects, does that mean you come of ...

TNF-α has proinflammatory effects on ... with a similar asthma phenotype. Dual inhibition of IL-4 and IL-13 with dupilumab represents a very promising avenue for biologic-based asthma therapy ...

An advance in therapy would be the development of more specific anti-asthma drugs that lack side effects. If such treatments could be taken orally, then they might also be applicable to the ...

The TGA has issued a requirement for new warnings to be provided with the drug montelukast, commonly used to treat asthma and hay fever.

For individuals with severe asthma, biologics—a new type of treatment targeting specific mechanisms in the immune system—have been shown to reduce asthma attacks, lower the need for ...

“Only 20 per cent of people who could benefit from biologics are actually ... minds have been damaged by steroid side effects ...

Most patients with HES are treated with high doses of corticosteroids, but many discontinue them owing to side effects ... of severe eosinophilic asthma. These biologics lower eosinophil numbers ...

Such an approach resulted in the development of biologics targeted ... effective in animal models of asthma. It is becoming apparent that significant clinical effects with anticytokine-based ...