Merck’s Keytruda holds on to the top spot while AbbVie’s Humira—once the world’s top-selling drug—continues to cede its ...

There are currently four monoclonal antibodies available that are directed against TNF: infliximab, adalimumab, golimumab and certolizumab. All of these agents are efficacious in RA, with clinical ...

The resulting paper, "HLA DQA1*05 and risk of anti-TNF treatment failure and anti-drug antibody development in children with Crohn's Disease," appears in the American Journal of Gastroenterology.

(In justifying to Centocor why it would be wise to invest in the development of antibodies to lymphotoxin and TNF, I mentioned the possibility of their therapeutic usefulness in autoimmune diseases.) ...

A study by Strangfeld et al. adds specificity by showing a moderately increased risk of herpes zoster in patients receiving anti-TNF antibody treatment, and raises the question of whether live ...

Since the 1990s, numerous studies have been performed to evaluate the effect of monoclonal antibodies on TNF-α and soluble receptor fusion proteins on cytokine levels and survival of septic patients.

The drug has the advantage of less frequent, once-monthly dosing compared to TNF antibodies and, theoretically at least, broader activity against TNF. Meanwhile, Telavant also has an option on a ...

The report covers 2024 sales data of innovator therapeutic antibodies and proteins, biosimilars and the novel biologic drug modalities gene & cell therapy ...

BALTIMORE--(BUSINESS WIRE)--TNF Pharmaceuticals, Inc. (Nasdaq: TNFA) (“TNF” or the “Company”), a clinical stage biopharmaceutical company committed to ...

Contrary to established dogma, the spleen is not the principal source of the pro-inflammatory cytokine called tumor necrosis factor (TNF), which drives the sort of system-wide inflammation seen in ...