Changes in blood are detectable at age 50 and universal by 60, paving the way for spotting early signs of unhealthy aging.

"Epigenetics tells a cell what kind of cell it ... shown for the first time that fat cells possess an epigenetic memory of ...

Rapa creates its therapies by harvesting T cells from the patient, applying its epigenetic reprogramming ... central and stem memory, sets Rapa apart from competing T cell therapies that typically ...

This deficiency prompts a shift from a reliance on AR signaling for cell ... cells can adapt through epigenetic reprogramming. In addition, the study demonstrates that inhibiting TET2 can reverse ...

Stem cells can produce any other cell type, it is just a matter of telling them in the right way. From a biological perspective, this means activating the proper genetic programme by pressing the ...

Cells are the smallest units of life. But even within the same tissue or organ, they are not all identical. New variations arise continuously during cell proliferation. While genetic mutations alter ...

stem cell aging, epigenetic regulation of stem cells and the development of CRISPR tools for editing the genome of HSCs and for modulating DNA methylation. Katherine King, M.D., Ph.D. began her own ...

To address these challenges, Professor Amrolia has developed a cutting-edge solution that preserves early “stem cell memory” T-cells, which persist longer in patients together with dual ...

Recently, CAR-T cell therapies have emerged ... Furthermore, during the peak expansion of T cells, there was a predominance of central memory T cells (TCM) and stem-like memory T cells (TSCM ...