This triggers a series of intracellular signaling pathways, which ultimately dictate the response of the T cell. The insights from computational models have greatly improved our understanding of the ...

Recent research points to the potential utility of a familiar sounding foe–herpes virus–in the fight against cancer.

A team identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival.

University of Michigan researchers have identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a ...

The Cocoon® (from Lonza) is a functionally closed, sterile, efficient manufacturing platform, which combined with our ...

An engineered viral protein enhanced the anticancer function of T cells in mice, suggesting a new strategy to improve ...

A novel machine learning model enhances colorectal cancer (CRC) prognosis and immunotherapy response prediction by ...

Oncogenic signaling pathways in cancer cells can disrupt ... the cellular and molecular mechanisms involved in intra-tumoral T-cell activation, especially in resistant tumors, remain unclear.

and the T cell is a really important immune cell, so it’s exciting that we’ve been able to connect this cell activation pathway that people think about a lot in T cells with this fundamental ...

Enzyme kinetic data from the BRENDA database were mapped onto the genome-scale metabolic model of Saccharomyces cerevisiae to ...

Without these inhibitory receptors, the immune response surges unchecked, leading to heightened inflammation, accelerated T-cell activation ... directed at this pathway could quiet the alarm ...