Methotrexate is a generic drug prescribed to treat certain types of cancers, arthritis, and psoriasis in adults and some children. As with other drugs, methotrexate can cause side effects, such as ...

These side effects can vary depending on what condition ... used in adults to treat psoriatic arthritis alone or with the drug methotrexate. Using Stelara with methotrexate may increase your ...

Leucovorin is commonly used to reduce toxicity, or potential side effects, after receiving a medicine called methotrexate at ... kill the cancer cells. Oral Tablet. Leucovorin should be stored ...

2003). HD-MTX used alone is associated with significantly fewer treatment-associated toxic side effects (DeAngelis & Hormingo; Plotkin & Batchelor; Yamanaka & Tanaka). Methotrexate is an ...

Nat Clin Pract Rheumatol. 2007;3(1):26-34. Slow transport via folate receptor (lower affinity for methotrexate than for folic acid) Increased drug efflux via ATP-binding cassette (ABC) subfamily ...