Alpha blockers are substances that antagonize alpha ... Tamsulosin and alfuzosin are less selective towards arterial alpha receptors and thus have less of a first dose-hypotension effect.

Carvedilol and labetalol are non-selective beta-blockers that also block alpha-1 receptors. Propranolol and metoprolol are lipid soluble beta-blockers and can be used to treat anxiety, migraine ...