Most recently an enzyme previously described as an archaeal FBP phosphatase in Thermococcus ... it catalyses the reaction following the class I mechanism 23 involving a lysine Schiff base 24,25.

discovered a new checkpoint mechanism that fine-tunes gene transcription. As reported in a study published in Cell, a component of the Integrator protein complex tethers the protein phosphatase 2A ...

Researchers from the Wistar Institute in Philadelphia and the Peter MacCallum Cancer Center in Melbourne, Australia, say they have discovered a new checkpoint mechanism that fine-tunes gene ...

The VSP's ability to tune phosphoinositide phosphatase activity by voltage will also serve as an important molecular tool to understand mechanisms of tumor suppressor phosphatase, PTEN ...

Smooth muscle, found in the walls of blood vessels and in internal organs such as lungs, stomach and the bladder, contracts as the end result of a series of chemical reactions. In a new study ...

This transformation, in which the hydroxy group on a single carbon flips from one stereochemical configuration to the other, seems like a simple epimerization, but the reaction is quite complicated.

This study will aim to characterize the role of Dusp4 in modulating the molecular mechanisms that regulate ... then inhibition of this dual-specificity phosphatase could prove beneficial in ...