1,2 Polymers such as albumin and chitosan have been used to prepare microspheres in different sizes to deliver drugs in a controlled fashion to the target organ. 3,4 Poly(DL-lactide-co-glycolide) ...

There are numerous drug-loaded PLGA microsphere formulations on the market. For instance, Lupron Depot ®, which contains leuprolide acetate enclosed in PLGA microspheres, is used to treat ...

High-performance liquid chromatography (HPLC) was recently used to detect acylated impurities in artificial hormones meant to ...

Emulsification, particularly the solvent evaporation method, stands out as a profoundly utilized technique in preparing PLGA microspheres. By employing single or double emulsification methods, both ...

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(PLGA)-encapsulated peptide mixture nanoparticles and PLGA microspheres as delivery systems for vaccines. PLGA polymers were used to form microspheres for a therapeutic vaccine against cervical ...

Then, there is a solvent-removal step to harden the newly-formed PLGA microspheres, and filtration (sieving) and rinsing steps to isolate PLGA microspheres of the desired size distribution while ...

More information: Meenakshi Kamaraj et al, Granular Porous Nanofibrous Microspheres Enhance Cellular Infiltration for Diabetic Wound Healing, ACS Nano (2024). DOI: 10.1021/acsnano.4c10044 ...

Polyglycolic and polylactic acid are biodegradable, thermoplastic materials that are used in a wide range of applications, particularly in biomedical applications such as medical implant hardware, ...