Take a grooved bar, for example, made of 4340 alloy steel with ultimate tensile strength ... material at fatigue loading with different notch factors. A stress riser is always a key factor ...

We have utilized both inhibitory and inductive signaling events to study the roles of different Notch pathway factors, and how they regulate the activity of resident tissue and cell identity genes.

Transcription factors are master regulators of cell state ... To determine whether SAHMs bind endogenous NOTCH proteins present in human T-ALL cells, we performed pull-down assays in KOPT-K1 ...

Verdine, PhD, Professor of Chemistry at Harvard University, published research in Nature entitled, “Direct Inhibition of the Notch Transcription Factor Complex.” Results presented in the paper showed ...